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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKACB
All Species:
15.45
Human Site:
S322
Identified Species:
30.91
UniProt:
P22694
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22694
NP_002722.1
351
40623
S322
F
I
P
K
F
R
G
S
G
D
T
S
N
F
D
Chimpanzee
Pan troglodytes
XP_001136448
346
40126
S317
F
I
P
K
F
R
G
S
G
D
T
S
N
F
D
Rhesus Macaque
Macaca mulatta
O62846
209
24077
T183
Q
Q
G
Y
L
Q
V
T
D
F
G
F
A
K
R
Dog
Lupus familis
XP_867543
351
40605
S322
F
I
P
K
F
R
G
S
G
D
T
S
N
F
D
Cat
Felis silvestris
Mouse
Mus musculus
P05132
351
40552
P322
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
Rat
Rattus norvegicus
P68182
351
40689
S322
F
I
P
K
F
R
G
S
G
D
T
S
N
F
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q6U1I9
432
48872
S381
N
P
N
V
S
G
P
S
D
L
R
H
F
D
P
Frog
Xenopus laevis
Q6GPN6
434
49096
S383
N
P
N
V
S
G
P
S
D
L
Q
H
F
D
P
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
T379
P
P
F
N
P
N
V
T
G
P
N
D
L
R
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P12370
353
40820
P324
F
I
P
R
C
K
G
P
G
D
T
S
N
F
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P21137
404
46327
N359
S
F
S
K
G
E
S
N
G
R
L
F
E
A
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06245
380
44201
G348
Y
E
P
P
I
T
S
G
I
G
D
T
S
L
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
47.8
98.8
N.A.
92
96.8
N.A.
N.A.
35.6
35.2
34.4
N.A.
82.1
N.A.
66.3
N.A.
Protein Similarity:
100
98
54.1
99.1
N.A.
95.1
98
N.A.
N.A.
54.6
55
54.2
N.A.
89.8
N.A.
77.4
N.A.
P-Site Identity:
100
100
0
100
N.A.
86.6
100
N.A.
N.A.
6.6
6.6
6.6
N.A.
73.3
N.A.
13.3
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
93.3
100
N.A.
N.A.
6.6
6.6
13.3
N.A.
86.6
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
46.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
65.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
25
50
9
9
0
17
50
% D
% Glu:
0
9
0
0
0
9
0
0
0
0
0
0
9
0
0
% E
% Phe:
50
9
9
0
42
0
0
0
0
9
0
17
17
50
9
% F
% Gly:
0
0
9
0
9
17
50
9
67
9
9
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
9
% H
% Ile:
0
50
0
0
9
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
0
0
0
50
0
17
0
0
0
0
0
0
0
9
0
% K
% Leu:
0
0
0
0
9
0
0
0
0
17
9
0
9
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
17
0
17
9
0
9
0
9
0
0
9
0
50
0
0
% N
% Pro:
9
25
59
9
9
0
17
17
0
9
0
0
0
0
17
% P
% Gln:
9
9
0
0
0
9
0
0
0
0
9
0
0
0
0
% Q
% Arg:
0
0
0
9
0
34
0
0
0
9
9
0
0
9
9
% R
% Ser:
9
0
9
0
17
0
17
50
0
0
0
50
9
0
0
% S
% Thr:
0
0
0
0
0
9
0
17
0
0
50
9
0
0
0
% T
% Val:
0
0
0
17
0
0
17
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _